Oregon Written Tattoo Practice Test

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A tan, brown, or black macule on the skin that may arise in pre-existing moles is indicative of which condition?

Squamous cell carcinoma
Nevus
Malignant Melanoma
Sebaceous

The correct answer is: Malignant Melanoma

A tan, brown, or black macule on the skin that may arise in pre-existing moles is indicative of malignant melanoma because this condition is characterized by changes in moles, including changes in color, shape, or size. Melanoma often develops from existing melanocytic lesions, which are moles. The macule, which is a flat, distinct, colored area of skin that is less than 1 centimeter wide, can show varied pigmentation, and its appearance, especially changes in pre-existing moles, serves as a warning sign for potential malignancy. Recognizing these changes is crucial because malignant melanoma can spread (metastasize) more aggressively than other forms of skin cancer, making early detection and diagnosis essential for effective treatment. In contrast, squamous cell carcinoma typically presents as a raised, scaly lesion rather than a flat macule. A nevus refers to a common mole, which is usually benign and does not imply malignancy. Sebaceous lesions are related to oil glands and are not indicative of cancer. Thus, the specific description of changes in pigmentation and the context of these changes align most closely with the characteristics of malignant melanoma.